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A 29 year old male patient presented with breathlessness and wet cough persisting since 4 years. It was only 1 year back that he consulted an allopathic doctor. Sputum culture and sensitivity test done isolated Pseudomonas aeruginosa. HRCT Lungs- Dense opacities with surroundings GGO with air bronchogram with in it noted apico basal segment of right lower lobe. Aspergillosis IgG was Positive with a reading of 45. Based on the clinical evaluation and the investigations, the biomedical diagnosis was made as Aspergillosis. He took conventional medicines for 6 months, but did not get relief. He now consulted Dr Rajnikanth for ayurvedic management. The ayurvedic diagnosis was Phuphusa gata krmi. The line of treatment followed was Krmi hara cikitsa. Strengthening the pranavaha srotas by including medicines indicated in shvasa roga was also a part of the treatment plan. With 1 month of Ayurvedic treatment, he got complete relief from all the symptoms. The Aspergillosis IgG became negative and the reading was 6.98U/ml. This case report demonstrates the standalone ayurvedic management of Aspergillosis in a patient who did not get relief despite taking conventional medicines.