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A 73-year-old female patient  presented with multiple joint pain on & off without any specific trigger factors for 4 years. Condition got aggravated in the last 1 year.  The associated symptoms are severe abdominal bloating, incomplete bowel evacuation even with laxatives and disturbed sleep. She is a known hypertensive, and is on regular allopathic medication. She took ayurvedic medicines for knee pain for 3 years and got significant relief. But for the presenting complaints, there has been no prior consultation or treatment. The patient approached Dr Partap Chauhan for better Ayurvedic management. On examination, there was pain and swelling in both knees. Based on the clinical examination and X-Ray of the knees findings, the biomedical diagnosis was made as Osteoarthritis and Ayurvedic diagnosis as sandhivata. The line of treatment followed was Vatanulomana, vatapitta shamana, sroto shodhana and ama pacana. Within 1 month of starting treatment, there was a significant reduction in pain and swelling. In 7 months, only mild constipation and bloating persisted. In 11 months, the dose of the anti-hypertensive drugs could be tapered. VAS recorded as 7 at baseline for multiple joint pain reduced to 2 at endpoint. In 1 year and 10 months, the patient got complete relief from all the symptoms. Repeated Xray taken revealed improvement. This case report demonstrates the integrative management of Osteoarthritis in a patient who had been suffering from this condition since 4 years and was worsening.