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A 43-year-old female patient presented with lower abdomen pain and burning sensation in urine since 15 days. The associated symptoms were frequent mouth ulcer since 2 years and irregular periods since 1 year. There were no prior consultations or treatments. The patient approached Dr Tara for ayurvedic management. Based on the clinical findings and USG report, the biomedical diagnosis was Multiple left renal calculi with mild hydronephrosis and the Ayurvedic diagnosis was Udavarta janya ashmari. The line of treatment followed basically targeted at strengthening the uterus and the pakvashaya. Pacification of Apanavayu dushti and Mustrashmari nashaka were also the targets of the treatment. Within 1 week of Ayurvedic treatments, the patient could get significant relief from the symptoms. The repeat USG done after 1 month of treatment, revealed only the 7 mm-sized calculus in the middle calyx, while the 6mm calculus in the upper calyx and 5 mm calculus in the lower calyx were not detected. Hydronephrosis is absent. This case report demonstrates the successful standalone ayurvedic management of Renal calculi.