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A 46-year-old female, diagnosed with Multiple sclerosis presented with difficulty in walking, writing, and fine movements asoociated with involuntary  nodding of the head since 2 years. The patient was normal until 14 years back. In 2008, she developed a sudden blurring of vision for which she took the standard of care. She was diagnosed with Retrobulbar neuritis. Etiological workup was done, and she was discharged. Based on MRI findings, she was provisionally diagnosed as Multiple Sclerosis. Her vision was recovered but had fatigue that she managed with home remedies. In 2009, the condition relapsed. The biomedical diagnosis was confirmed as Relapsing-remitting Multiple sclerosis with Brain MRI. By 2014, the patient developed difficulty in writing, she noticed that her handwriting started changing. By 2019, the symptoms worsened, and she developed nodding of head, an inability to walk and repeated episodes of tremors. In spite of taking conventional medicines, the outcome was not satisfactory. In 2021, she consulted Dr Shibu Varghese. The ayurvedic diagnosis was Vatavyadhi. The line of treatment followed was to correct dhatvagni, adopt dhatugata and sannipata jvara cikitsa, use of tikta rasa followed by madhura rasa and rasayana cikitsa. The outcomes were assessed based on EDS Scale, Ambulation Index, and Neurologic physical examination. After 2 weeks of treatment, patient could walk without support. The frequency of head nodding reduced, handwriting of the patient has improved. The EDS scale that was 7 before treatment became 2 after ayurvedic treatment. The ambulation index was recorded 2 pre-treatments became 0 after treatment. The patient is continuing the medicines and advised to come for regular follow ups.