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    A 9-year-old female patient presented with right upper abdominal pain which lasted for few hours since 3-4 months. She was given analgesics to relieve pain. The pain was persisting, and USG done confirmed the Biomedical diagnosis as cholelithiasis. When the pain reoccurred, the patient opted for Ayurveda and consulted Dr Rajnikanth. The ayurvedic diagnosis was Pittashaya ashmari. The line of treatment followed was pitta hara and shotha hara. The target of the medicines was lekhana karma, to help eliminate the ashmari in the pittashaya. Three days after starting the Ayurvedic treatment, the pain reduced, and the tenderness was absent in the epigastric region. After 1 month of treatment, the patient had complete relief from the symptoms. Repeat USG done after treatment shows no significant abnormality.

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      A 9-year-old female patient presented with right upper abdominal pain which lasted for few hours since 3-4 months. She was given analgesics to relieve pain. The pain was persisting, and USG done confirmed the Biomedical diagnosis as cholelithiasis. When the pain reoccurred, the patient opted for Ayurveda and consulted Dr Rajnikanth. The ayurvedic diagnosis was Pittashaya ashmari. The line of treatment followed was pitta hara and shotha hara. The target of the medicines was lekhana karma, to help eliminate the ashmari in the pittashaya. Three days after starting the Ayurvedic treatment, the pain reduced, and the tenderness was absent in the epigastric region. After 1 month of treatment, the patient had complete relief from the symptoms. Repeat USG done after treatment shows no significant abnormality.

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    TITLE OF CASE

    Standalone successful Ayurvedic management of cholelithiasis- A case report

    Dr Rajnikanth 

    ABSTRACT

    A 9-year-old female patient presented with right upper abdominal pain which lasted for few hours for 3-4 months. She was given analgesics to relieve pain. The pain was still persisting, and USG done confirmed the Biomedical diagnosis as cholelithiasis. When the pain reoccurred, the patient opted for Ayurveda and consulted Dr Rajnikanth. The ayurvedic diagnosis was Pittashaya ashmari. The line of treatment followed was pitta hara and shotha hara. The target of the medicines was lekhana karma, to help eliminate the ashmari in the pittashaya. Three days after starting the Ayurvedic treatment, the pain reduced, and the tenderness was absent in the epigastric region. After 1 month of treatment, the patient had complete relief from the symptoms. Repeat USG done after treatment shows no significant abnormality.

    KEYWORDS

    Gallbladder, cholelithiasis, ashmari, pittashaya, case report, standalone

    INTRODUCTION

    Gallstones are hardened deposits of digestive fluid that can form in your gallbladder. Your gallbladder is a small, pear-shaped organ on the right side of your abdomen, just beneath your liver. The gallbladder holds a digestive fluid called bile that's released into your small intestine. Gallstones are hardened deposits of bile that can form in the gallbladder. Bile is a digestive fluid produced in the liver and stored in gallbladder. When we eat, the gallbladder contracts and empties bile into the small intestine (duodenum). Gallstones range in size from as small as a grain of sand to as large as a golf ball. Some people develop just one gallstone, while others develop many gallstones at the same time.

    Symptoms- Gallstones may cause no signs or symptoms. If a gallstone lodges in a duct and causes a blockage, the resulting signs and symptoms may include: 

    Sudden and rapidly intensifying pain in the upper right portion of your abdomen 

    Sudden and rapidly intensifying pain in the centre of your abdomen, just below your breastbone 

    Back pain between your shoulder blades 

    Pain in your right shoulder 

    Nausea or vomiting 

    Gallstone pain may last several minutes to a few hours.

    Causes: An exact cause is not being defined. But, some factors identified are when the bile contains too much cholesterol or bilirubin, or when the bladder does not empty the contents correctly.

    Types of gallstones: There are different type of gall stones depending on the depending on the appearance and the composition. 

    Cholesterol gallstones. The most common type of gallstone, called a cholesterol gallstone, often appears yellow in colour. These gallstones are composed mainly of undissolved cholesterol, but may contain other components. 

    Pigment gallstones. These dark brown or black stones form when your bile contains too much bilirubin.

    Complications: Complications may include 

    Inflammation of the gallbladder.

    Blockage of the common bile duct.

    Blockage of the pancreatic duct.

    Gallbladder cancer. 

    Diagnostic criteria- Medical history taking and clinical evaluation are the basic diagnostic criteria, followed. Apart from this the general technique followed are Abdominal and Endoscopic Ultrasound, Imaging like HIDA, CT, MRCP, ERCP, are used two understand the intensity of the problem. Blood tests are done to identify or rule out any infections.

    Prognosis & Treatment available: Most people with gallstones that don't cause symptoms will never need treatment. Your doctor will determine if treatment for gallstones is indicated based on your symptoms and the results of diagnostic testing. The doctor may recommend that you be alert for symptoms of gallstone complications, such as intensifying pain in your upper right abdomen. If gallstone signs and symptoms occur in the future, you can have treatment. 

    Treatment options for gallstones include: 

    Surgery to remove the gallbladder (cholecystectomy). 

    Medications to dissolve gallstones. 

    Laparoscopic cholecystectomy

    PATIENT INFORMATION

    In this case report, a 9-year-old female patient presented with right upper abdominal pain which lasted for few hours since 3-4 months. She was given analgesics to relieve pain. The pain was still persisting, and USG done confirmed the Biomedical diagnosis as cholelithiasis. When the pain reoccurred, the patient opted for Ayurveda and consulted Dr Rajnikanth.

    No relevant family/surgical/psychosocial/genetic history.

    Addictions- Nil

    CLINICAL FINDINGS

    Per abdominal examination done- Mild tenderness- in right epigastric area 

    TIMELINE

    Image 1. Timeline of events added below

    cholelithiasis.jpg

    DIAGNOSTIC ASSESSMENT

    Modern Diagnostic parameter; The condition was pre diagnosed as Cholelithiasis based on the presenting complaints and the USG report. 

    Image 2. USG done at Baseline dated 21.3.2023

    baseline_usg_report_dated_21_3_2023.png

    Ayurvedic Assessment was done based on the presenting complaints, and the clinical evaluation. 

    Differential Diagnosis- 

    Acute Pancreatitis

    Appendicitis

    Bile Duct Strictures
    Peptic Ulcer Disease
    Gallbladder Cancer
    Irritable bowel syndrome
    Based on the USG report and clinical evaluation, the the diagnosis was confirmed as Cholelithiasis. 

    Prognosis & Treatment available: Management of gallstones depends on the symptoms and the age of the patient. In children, symptomatic gallstones need cholecystectomy. This patient had tried analgesics for 3-4 months prior to confirmation of diagnosis, but pain always recurred. Three days after the initiation of Ayurvedic treatment, the pain reduced and the tenderness was absent in the epigastric region. After 1 month of treatment, the patient attained complete relief from the symptoms.

    THERAPEUTIC INTERVENTION

    Please refer the tab ‘Treatment’ in the Portal. 

    FOLLOW-UP AND OUTCOMES

    Both objective and subjective parameters were assessed to analyse the outcome of the ayurvedic treatment. 

    Subjective parameters: Three days after the initiation of Ayurvedic treatment, the pain reduced and the tenderness was absent in the epigastric region. After 1 month of treatment, the patient attained complete relief from the symptoms.

    Objective parameters:  Repeat USG was done at endpoint, detected no cholelithiasis. 

    Clinician-based assessment; Symptoms during the treatment were assessed to analyse the outcome of the treatment. 

    Patient-assessed; Not relevant

    Endpoint Evaluation:

    Image 3. USG at endpoint dated 29.4.2023

    endpoint_usg_dated_29_4_2023.png

    Intervention adherence and tolerability – The patient adhered to the prescribed treatments and tolerated the treatments well. 

    Method of assessment- By monitoring the patient.

    Adverse and unanticipated events; None reported

    DISCUSSION: 

    Management of gallstones depends on the symptoms and the age of the patient. In children, symptomatic gallstones need cholecystectomy. This patient had tried analgesics for 3-4 months prior to confirmation of diagnosis, but pain always recurred. The ayurvedic diagnosis was Pittashaya Ashmari and the medicines and therapies chosen were pitta hara and shotha hara. Lekhana dravya were included to help eliminating the ashmari. 

    PATIENT’S PERSPECTIVE

    Not available. 

    LEARNING POINTS/TAKE HOME MESSAGES 

    This patient being a child of 9 years, her parents did not want surgery as recommended by the allopathic doctor and so ayurveda proved to be a perfect alternative to help the patient become free from her symptoms, and the calculi could be eliminated completely with Ayurvedic treatments. 

    INFORMED CONSENT

    Written consent obtained from patient for publishing of the case report in the Portal

    ACKNOWLEDGEMENTS

    None specified

    CONFLICT OF INTEREST

    None declared.

    FUNDING

    None

    REFERENCE

    1. https://www.mayoclinic.org/diseases-conditions/gallstones/diagnosis-treatment/drc-20354220

     

  • Immersive Learning

    • Modern Diagnosis

      BIOMEDICAL DIAGNOSIS: Cholelithiasis

      ABOUT THE DISEASE: 

      Gallstones are hardened deposits of digestive fluid that can form in your gallbladder. Your gallbladder is a small, pear-shaped organ on the right side of your abdomen, just beneath your liver. The gallbladder holds a digestive fluid called bile that's released into your small intestine. Gallstones are hardened deposits of bile that can form in the gallbladder. Bile is a digestive fluid produced in the liver and stored in gallbladder. When we eat, the gallbladder contracts and empties bile into the small intestine (duodenum). Gallstones range in size from as small as a grain of sand to as large as a golf ball. Some people develop just one gallstone, while others develop many gallstones at the same time.

      Symptoms- Gallstones may cause no signs or symptoms. If a gallstone lodges in a duct and causes a blockage, the resulting signs and symptoms may include: 

      Sudden and rapidly intensifying pain in the upper right portion of your abdomen 

      Sudden and rapidly intensifying pain in the centre of your abdomen, just below your breastbone 

      Back pain between your shoulder blades 

      Pain in your right shoulder 

      Nausea or vomiting 

      Gallstone pain may last several minutes to a few hours.

      Causes: An exact cause is not being defined. But, some factors identified are when the bile contains too much cholesterol or bilirubin, or when the bladder does not empty the contents correctly.

      Types of gallstones: There are different type of gall stones depending on the depending on the appearance and the composition. 

      Cholesterol gallstones. The most common type of gallstone, called a cholesterol gallstone, often appears yellow in color. These gallstones are composed mainly of undissolved cholesterol, but may contain other components. 

      Pigment gallstones. These dark brown or black stones form when your bile contains too much bilirubin.

      Complications: Complications may include 

      Inflammation of the gallbladder.

      Blockage of the common bile duct.

      Blockage of the pancreatic duct.

      Gallbladder cancer. 

      Diagnostic criteria- Medical history taking and clinical evaluation are the basic diagnostic criteria, followed. Apart from this the general technique followed are Abdominal and Endoscopic Ultrasound, Imaging like HIDA, CT, MRCP, ERCP, are used two understand the intensity of the problem. Blood tests are done to identify or rule out any infections. 

      In this case report, a 9-year-old female patient presented with right upper abdominal pain which lasted for few hours since 3-4 months. She was given analgesics to relieve pain. The pain was still persisting, and USG done confirmed the Biomedical diagnosis as cholelithiasis. When the pain reoccurred, the patient opted for Ayurveda and consulted Dr Rajnikanth.

      Image 1. USG report at baseline dated 21.3.2023

      baseline_usg_report_dated_21_3_2023.png

      Prognosis & Treatment available: Most people with gallstones that don't cause symptoms will never need treatment. Your doctor will determine if treatment for gallstones is indicated based on your symptoms and the results of diagnostic testing. The doctor may recommend that you be alert for symptoms of gallstone complications, such as intensifying pain in your upper right abdomen. If gallstone signs and symptoms occur in the future, you can have treatment. 

      Treatment options for gallstones include: 

      Surgery to remove the gallbladder (cholecystectomy). 

      Medications to dissolve gallstones. 

      Laparoscopic cholecystectomy

      Reference

      1. https://www.mayoclinic.org/diseases-conditions/gallstones/diagnosis-treatment/drc-20354220
    • Ayurveda Diagnosis

      AYURVEDIC DIAGNOSIS: Pittashaya Ashmari

      About Ashmari: 

      The term ‘ashmari’ stands for Calculi. In the classical textbooks of Ayurveda, the explanation of ashmari is about the calculus that is found in the kidney. The nidan, purvarupa, lakshana and chikitsa are all explained pertaining to the renal calculi. There is no direct correlation with gall stones in the classical textbooks. Hence when there is a biomedical diagnosis of Gall stones also called as Cholelithiasis, the clinicians have extended the term ‘ashmari’ here also. 

      The purvarupa, and lakshana mentioned in the classical textbooks is specific to the mutrashmari. 

      सामान्यलिङ्गं रुङ् नाभि सीवनिवस्तिमूर्धसु । विशीर्णधारं मूत्रं स्यात्तया मार्गे निरोधिते ॥

      तद्व्यापायात्सुखं मेहेदच्छं गोमेदकोपमं । तड् सङ्क्षोभात् क्षते सास्रमायाच्चातिरुग्भवेत् ॥ (Va.Ni.A.9)

      So they cannot be taken into consideration here. But pain is a key factor, that can be seen in calculus. 

      Regarding Pittashaya: Liver is generally referred to as Pittashaya. Yakrt is the Mula for raktavaha srotas. Here, pitta is the predominant dosa, and as far as gall stones are concerned as the sthana is yakrt ie…pittashaya the treating physician has confirmed the diagnosis as Pittashaya ashmari. 

      In this case report, a 9-year-old female patient presented with right upper abdominal pain which lasted for few hours since 3-4 months. She was given analgesics to relieve pain. The pain was still persisting, and USG done confirmed the Biomedical diagnosis as cholelithiasis. When the pain reoccurred, the patient opted for Ayurveda and consulted Dr Rajnikanth.

      The line of treatment mentioned  by Sushruta for Ashmari is as follows:

      Apakarshana –Shasta karma (Surgical intervention)

      Prakrutivighatana – Shodhana and Shamana 

      Nidana parivarjana – Avoidance of causative factors

      Shamanoushadhis: which are selected in Ashmari should have the following properties- Kaphahara , Mutra virechana and Apana vayu anulomana.

      Treatment & rationale for treatment: This disease being a correlation by the treating physician depending on the presenting complaints, and the confirmed Biomedical diagnosis, a treatment was planned by the physician according to his yukti and the rationale has been explained as follows. 

      Table 1. Medicines/therapies and the rationale of the treatment

       

      Name of the medicine/ Procedure

      Rationale

      Pittahara vati

      To reduce pitta dosha locally in the gall bladder.

      Trivikram rasa

      Acts as lekhana karma for ashmari in pittashaya.

      Distone syrup

      Acts as lekhana karma for ashmari in pittashaya.

      Distone Tablet

      Acts as lekhana karma for ashmari in pittashaya.

      Sharpunkha and Bhumiamlaki lepa

       

      To reduce shotha locally.

      Sadhyasadhyata: The sadhyasadhyata of Ashmari has been explained in the classical textbooks, they cannot be applied here to Pittashaya Ashmari. Hence the treatment to be done to pacify the condition. 

      Reference

      1. Madhava Nidana. Chapter 32. Ashmari Nidanam. 

       

       

    • Treatment

      Name of Medicine Dosage Form Dosage Mode of Administrtation From - To (Date) Medicine Reference
      Pittahara vati Vati 1 Tablet Oral with warm water thrice a day 2023-03-27 - 2023-05-13 Patent and Proprietary Medicine
      Trivikram rasa Tablet 1 Tablet Oral with warm water twice a day 2023-03-27 - 2023-05-13 Sharangadhara Samhita. Madhyamakhanda 12.172 - 174
      Distone syrup Syrup 10 ml Oral, twice a day 2023-03-27 - 2023-05-13 Patent and Proprietary Medicine
      Distone Tablet 1 Tablet 10 ml Oral, thrice a day 2023-03-27 - 2023-05-13 Patent and Proprietary Medicine
      Sharapunkha and Bhumyamlaki Lepa Required Quantity Applied externally on the epigastric region 2023-03-27 - 2023-05-13 Anubhuta Yoga
    • Outcome Measures

      In this case report, a 9-year-old female patient presented with right upper abdominal pain which lasted for few hours since 3-4 months. She was given analgesics to relieve pain. The pain was still persisting, and USG done confirmed the Biomedical diagnosis as cholelithiasis. When the pain reoccurred, the patient opted for Ayurveda and consulted Dr Rajnikanth.

      Assessment: Both objective and subjective parameters were assessed to analyse the outcome of the ayurvedic treatment. 

      Subjective parameters: After 1 week of starting ayurvedic treatments, he got significant relief from pain. After 1 month of treatment, there is no pain and tenderness. After 1 and half months, the patient got complete relief from the symptoms.  

      Objective parameters: Repeat USG done at endpoint did not detect Cholelithiasis.  

      Image 1. USG at endpoint dated 29.4.2023

      endpoint_usg_dated_29_4_2023.png

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